Three young children and two adults were transported to Bay Area hospitals after the minivan they were riding in left the roadway and crashed into a sign, guardrails and a large tree stump along Highway 221 in south Napa County about noon on Thursday, according to the California Highway Patrol.
The 2008 Chevrolet Uplander was travelling northbound on Highway 221 south of Anderson Road when, for an unknown reason, the van veered off the roadway, eventually crashing into a large eucalyptus stump in the center divide, Officer Marc Renspurger said.
The five occupants were taken to different hospitals after sustaining moderate to major injuries, Renspurger said.
The two adults were taken to Queen of the Valley Medical Center.
A 7-year-old passenger was transported to UC Davis Medical Center, a 4-year-old to Children's Hospital Oakland, and a 2-year-old passenger to the Queen.
Officials do not yet know why the vehicle veered off the roadway, but, Renspurger said, no car seats were inside the vehicle.
"All three kids should have been in car seats," he said.
Southbound lanes were closed and traffic was diverted to Napa Valley Corporate Way for about an hour. One northbound lane was also temporarily closed.